Department Chairmen

Professor LEUNG Tak Yeung

Department of Obstetrics and Gynaecology

Professor LEUNG Tak Yeung

Department of Obstetrics and Gynaecology

Contact Information
Office : (852) 3505-2805
Email :

Fetoscopic laser therapy for Twin-twin transfusion syndrome
Radiofrequency ablation of umbilical cord for fetal reduction
External cephalic version for breech presentation
Clinical application of array genomic comparative hybridization for prenatal genomic diagnosis
Clinical application of maternal circulating cell-free fetal DNA for prenatal diagnosis of chromosomal abnormalities
Prenatal screening of Down syndrome and Fragile X disease

Education and Qualifications

Research Interests
Special interest is in perinatal medicine, prenatal screening and diagnosis of fetal abnormalities, with advanced genetic and ultrasound technology, including the non-invasive prenatal diagnosis using maternal cell-free fetal DNA and array comparative genomic hybirdisation.
Prenatal diagnosis and screening
Twin pregnancy
Preterm delivery
Fetal growth restriction
External cephalic version
Information technology

Related Academic Programmes and Courses
HA Commission Training Course
The PROMPT Course (PRactical Obstetric Multi-Professional Training)
Certificate Course in Clinical Genetics
Selected Publications
  1. Leung TY, Qu JZ, Liao GJ, Jiang P, Cheng YK, Chan KC, Chiu RW, Lo YM. Noninvasive twin zygosity assessment and aneuploidy detection by maternal plasma DNA sequencing. Prenat Diagn 2013; 33:675-81.
  2. Qu JZZ, Leung TY (co-1st author), Jiang P, Liao GJW, Cheng YKY, Sun H, Chiu RWK, Chan KCA, Lo YM. Noninvasive Prenatal Determination of Twin Zygosity by Maternal Plasma DNA Analysis. Clin Chem 2013; 59:427-35.
  3. Leung TY, Vogel I, Lau TK, Chong W, Hyett JA, Petersen OB, Choy KW. Identification of submicroscopic chromosomal aberrations in fetuses with increased nuchal translucency and an apparently normal karyotype. Ultrasound Obstet Gynecol 2011; 38: 314-319.
  4. Leung TY, Stuart O, Suen S, Sahota D, Lau TK, Lao T. Comparison of perinatal outcomes of shoulder dystocia alleviated by different type and sequence of manoeuvres: a retrospective review BJOG 2011; 118: 985-990
  5. Leung TY, Stuart O, Sahota DS, Suen SS, Lau TK, Lao TT. Head-to-body delivery interval and risk of fetal acidosis and hypoxic ischaemic encephalopathy in shoulder dystocia: a retrospective review. BJOG 2011; 118:474-479.
  6. Leung TY, Chung PW, Rogers MS, Sahota DS, Lao TT, Chung TK. Urgent Cesarean delivery for fetal bradycardia. Obstet Gynecol 2009; 114: 1023-1028.
  7. Leung TY, Chan LW, Law LW, Sahota DS, Fung TY, Leung TN, Lau TK.  First trimester combined screening for Trisomy 21 in Hong Kong: outcome of the first 10000 cases. J Matern Fetal Neonat Med 2009; 22: 300-304.
  8. Leung TY, Leung TN, Sahota DS, Chan OK, Chan LW, Fung TY, Lau TK.  Obesity. Trends in maternal obesity and associated risks of adverse pregnancy outcomes in a population of Chinese women. BJOG 2008; 115: 1529-1537.
  9. Chiu RW, Chan KC, Gao Y, Lau VY, Zheng W, Leung TY, Foo CH, Xie B, Tsui NB, Lun FM, Zee BC, Lau TK, Cantor CR, Lo YM. Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma. Proc Natl Acad Sci USA 2008; 105: 20458-20463.
  10. Leung TY, Tam WH, Leung TN, Lok I, Lau TK. Effect of twin-to-twin delivery interval on umbilical cord blood gas in the second twins. Br J Obstet Gynaecol 2002; 109: 63-67
Junior Vice President of Hong Kong College of Obstetricians & Gynaecologists
Chairman of Prenatal Maternal Screening Special Interest Group, International Society for Prenatal Diagnosis
Professor in The CUHK-BGI Innovation Institute of Trans-omic
Member of Midwives Council of Hong Kong
Editorial Board member of American Journal of Perinatology, and Pediatric Research (Fetus & Pregnancy Section)
Foundation Board Member of Global Obstetric Network (GONet)
Foundation Secretary of The Chinese Fetal Medicine Foundation
Honorary Treasurer The Obstetrical and Gynaecological Society of Hong Kong
Vice-President The Obstetrical and Gynaecological Society of Hong Kong
Council Member of The Obstetrical and Gynaecological Society of Hong Kong
Board Member of Advanced Life Support in Obstetrics (ALSO) Hong Kong
Visiting Professor, Department of Obstetrics and Gynaecology, Guangzhou Medical University
Visiting Professor, Department of Obstetrics and Gynaecology, Hainan Medical College