Leung Tak Yeung

Department Chairmen

Professor LEUNG Tak Yeung

Department of Obstetrics and Gynaecology

Professor LEUNG Tak Yeung

Department of Obstetrics and Gynaecology

Contact Information
Office : (852) 3505-2805
Email : tyleung@cuhk.edu.hk

Fetoscopic laser therapy for Twin-twin transfusion syndrome
Radiofrequency ablation of umbilical cord for fetal reduction
External cephalic version for breech presentation
Clinical application of array genomic comparative hybridization for prenatal genomic diagnosis
Clinical application of maternal circulating cell-free fetal DNA for prenatal diagnosis of chromosomal abnormalities
Prenatal screening of Down syndrome and Fragile X disease

Education and Qualifications

Research Interests
Special interest is in perinatal medicine, prenatal screening and diagnosis of fetal abnormalities, with advanced genetic and ultrasound technology, including the non-invasive prenatal diagnosis using maternal cell-free fetal DNA and array comparative genomic hybirdisation.
Prenatal diagnosis and screening
Twin pregnancy
Preterm delivery
Fetal growth restriction
External cephalic version
Information technology

Related Academic Programmes and Courses
MSc in Medical Genetics
MSc in Obstetrics and Midwifery
SOPHIE: Safe Obstetric Practice for High Risk and Emergencies
Selected Publications
  1. Dong Z, Wang H, Chen H, Jiang H, Yuan J, Yang Z, Wang WJ, Xu F, Guo X, Cao Y, Zhu Z, Geng C, Cheung WC, Kwok YK, Yang H, Leung TY, Morton CC, Cheung SW, Choy KW. Identification of balanced chromosomal rearrangements previously unknown among participants in the 1000 Genomes Project: implications for interpretation of structural variation in genomes and the future of clinical cytogenetics Genet Med in press
  2. Cheng YKY, Leung TY, Law LW, Ting YH, Law KM, Sahota DS. First trimester screening for pre-eclampsia in Chinese pregnancies: Case control study. BJOG 2018 Mar;125(4):442-449.
  3. Khaw KS, Lee SW, Ngan Kee WD, Law LW, Lau TK, Ng FF, Leung TY. Randomized trial of anaesthetic interventions in external cephalic version for breech presentation. Br J Anaesth. 2015 Jun;114(6):944-50.
  4. Hui SY, Chor CM, Lau TK, Lao TT, Leung TY. Cerclage Pessary for Preventing Preterm Birth in Women with a Singleton Pregnancy and a Short Cervix at 20 to 24 Weeks: A Randomized Controlled Trial. Am J Perinatol 2013; 30:283-8.
  5. Leung TY, Qu JZ, Liao GJ, Jiang P, Cheng YK, Chan KC, Chiu RW, Lo YM. Noninvasive twin zygosity assessment and aneuploidy detection by maternal plasma DNA sequencing. Prenat Diagn 2013; 33:675-81.
  6. Leung TY, Vogel I, Lau TK, Chong W, Hyett JA, Petersen OB, Choy KW. Identification of submicroscopic chromosomal aberrations in fetuses with increased nuchal translucency and an apparently normal karyotype. Ultrasound Obstet Gynecol 2011; 38: 314-319.
  7. Leung TY, Stuart O, Sahota DS, Suen SS, Lau TK, Lao TT. Head-to-body delivery interval and risk of fetal acidosis and hypoxic ischaemic encephalopathy in shoulder dystocia: a retrospective review. BJOG 2011; 118:474-479.
  8. Leung TY, Chung PW, Rogers MS, Sahota DS, Lao TT, Chung TK. Urgent Cesarean delivery for fetal bradycardia. Obstet Gynecol 2009; 114: 1023-1028.
  9. Leung TY, Leung TN, Sahota DS, Chan OK, Chan LW, Fung TY, Lau TK. Obesity. Trends in maternal obesity and associated risks of adverse pregnancy outcomes in a population of Chinese women. BJOG 2008; 115: 1529-1537.
  10. Chiu RW, Chan KC, Gao Y, Lau VY, Zheng W, Leung TY , Foo CH, Xie B, Tsui NB, Lun FM, Zee BC, Lau TK, Cantor CR, Lo YM. Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma. Proc Natl Acad Sci USA 2008; 105: 20458-20463.
Senior Vice President of Hong Kong College of Obstetricians & Gynaecologists 2017-present
Scientific Editor of British Journal of Obstetrics and Gynaecology 2016-present