What are you looking for?
Start main content
Professor CHAN Ka Leung, Francis, SBS, JP

Professor CHAN Ka Leung, Francis, SBS, JP


Choh-Ming Li Professor of Medicine and Therapeutics

Contact Information

CUHK Employment
  • Dean, Faculty of Medicine
  • Choh-Ming Li Professor of Medicine and Therapeutics
  • Director, Centre for Gut Microbiota Research


  • Peptic ulcer bleeding
  • Helicobacter pylori
  • Endoscopic therapy
  • Colorectal cancer


Education & Qualifications


Research Interests
  • Peptic ulcer bleeding
  • Helicobacter pylori
  • Endoscopic therapy
  • Colorectal cancer


Additional Information

Award & Honour

  • ExpertScape Named Top 0.06% World Expert in Aspirin, Helicobacter Infections and Peptic Ulcer, 2019

  • Honorary Doctorate Degree, Osaka City University, 2018

  • Honorary Fellow of Internal Medicine, Royal College of Physicians of Thailand, 2018
  • International Leadership Award, The American College of Gastroenterology, 2018
  • 27th Seah Cheng Siang Memorial Lecturer, 2017
  • 19th Vikit Viranuvatti’s Lecturer, 2016
  • JGHF Marshall and Warren Lecturer, 2011
  • Andy Martynoga Memorial Lecturer, 2008
  • Croucher Senior Medical Research Fellowship, 2007-2008
  • The State Scientific and Technological Progress Award, National Office for Science and Technology Awards of PRC, 2007
  • David Y. Graham Lecturer, The American College of Gastroenterology, 2005


Professional Service

  • Board Member, Hong Kong Hospital Authority
  • MemberColorectal Cancer Screening Pilot Programme Task Force, Department of Health
  • Permanent Member, Expert Panel of Central Research Working Group for Hospital Authority, Chinese Medicine Research, Hong Kong Hospital Authority
  • Member, Governing Board, Hong Kong Jockey Club Disaster Preparedness and Response Institute, Hong Kong Academy of Medicine
  • Convenor, Endoscopy Task Force of Project Steering Committee on Standards for Ambulatory Facilities, Department of Health
  • Ex-officio Member, Research Fellowship Assessment Panel, Food and Health Bureau
  • Member (Oct 2017 – Sep 2020), External Review Committee, Hong Kong Sanatorium & Hospital
  • Honorary Advisor, Hong Kong Association for Integration of Chinese-Western Medicine
  • Advisor on Education, Peking Union Medical College (PUMC) 
  • Assessment  Expert of Health Research Projects (Mar 2013 – Feb 2016), Technology Education Unit of Ministry of Health of PRC 
  • Panelist, Global Panel of Clinicians and Clinical Researchers, Nature [to help Nature select a list of high-quality clinical journals for inclusion in the Nature Index]
  • Nominator, 2016 Future Science Prize, Beijing, China
  • External Assessor in Gastroenterology, University of Malaya, Malaysia
  • Leader, Task Force for Developing Clinical Practice Guidelines for Clinicians in Asia Pacific Countries, appointed by Asian Pacific Association of Gastroenterology and the Asian Pacific Society of Digestive Endoscopy
  • Member (Jul 2018 – Apr 2021), Open Fund Large Collaborative Grant Review Panel, National Medical Research Council, Ministry of Health, Singapore


Brief CV


Selected Publications


Professor Chan has published more than 500 full scientific articles in high impact factor international journals such as New England Journal of Medicine, Lancet and Gastroenterology with an H-index 94.


  1. Chan FK, et al. Risk of Postpolypectomy Bleeding With Uninterrupted Clopidogrel Therapy in an Industry-Independent, Double-Blind, Randomized Trail.  Gastroenterology 2019;156:918-925.
  2. Chan FK, et al. Management of patientsw on antithrombotic agents undergoing emergency and elective endoscopy: joint Asian Pacific Association of Gastroenterologyt (APAGE) and Asian Pacific Society for Digestive Endoscopy (APSDE) practice guidelines.  Gut 2018;67:405-417.
  3. Chan FK, et al. Gastrointestinal safety of celecoxib versus naproxen in patients with cardiothrombotic diseases and arthritis after upper gastrointestinal bleeding (CONCERN): an industry-independent, double-blind, double-dummy, randomised trial. Lancet 2017;389:2375-82.
  4. Chan FK, et al. Celecoxib versus omeprazole and diclofenac in patients with osteoarthritis and rheumatoid arthritis (CONDOR): arandomised trial. Lancet 2010;376:173-9.
  5. Chan FK, et al. Combination of a cyclo-oxygenase-2 inhibitor and a proton-pump inhibitor for prevention of recurrent ulcer bleeding in patients at very high risk: a double-blind, randomised trial. Lancet 2007;369:1621-6.
  6. Chan FK, et al. Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding. N Engl J Med 2005;352:238-44.
  7. Chan FK, et al. Eradication of Helicobacter pylori and the risk of peptic ulcers in patients starting long-term treatment with non-steroidal anti-inflammatory drugs: A randomised trial. Lancet 2002;359:9-13.
  8. Chan FK, et al. Celecoxib versus diclofenac and omeprazole in reducing the risk of recurrent ulcer bleeding in patients with arthritis. N Engl J Med 2002;347:2104-10.
  9. Chan FK, et al. Preventing recurrent upper gastrointestinal bleeding in patients with Helicobacter pylori infection who are taking low-dose aspirin or naproxen. N Engl J Med 2001;344:967-73.
  10. Chan FK, et al. Randomised trial of eradication of Helicobacter pylori before non-steroidal anti-inflammatory drug therapy to prevent peptic ulcers. Lancet 1997;350:975-97.