Professor LUI Oi Lan, Kathy
Assistant Dean (Research)
Professor, Department of Chemical Pathology
CUHK Employment
- Assistant Dean (Research)
- Professor, Department of Chemical Pathology
- Co-director, CAS CEMCS-CUHK Joint Laboratory for Cardiovascular Sciences
Expertise
- Cardiovascular diseases
- Immunology
Education & Qualifications
B.Sc. (CUHK), M.Phil. (CUHK), D.Phil. (Oxon)
Research Interests
- Cardiovascular Immunology
- Cardiovascular Repair and Regeneration
- Molecular mechanisms driving cardiovascular disease progression
Additional Information
Award and Honour
- RGC Research Fellowship, Research Grants Council of Hong Kong, 2022
- Excellent Young Scientists Fund, National Natural Science Foundation of China, 2019
- Founding Member, Young Academy of Sciences of Hong Kong, 2018
- Croucher Innovation Awards, 2017
Professional Service
- Editorial Board Member, Circulation Research, since 2023
- Editorial Board Member, Cardiovascular Research, since 2021
Academic Engagement in CUHK
- Postgraduate supervisor, MPhil / PhD in Chemical Pathology
Selected Publications
ORCID ID: 0000-0002-1616-3643
Web of science: AAC-8303-2020
- Qu H, Ho CK, Liu J, Cui L, Hou Y, Liang C, Ye W, Wong RHL, Hori S, Zhou B, Lui KO*. (2026) CD4+ Tregs drive post-ischemic sprouting angiogenesis via endothelial YY1/MAML1 reactivation. Advanced Science20:e18564
- Cui L, Ho CK, Liang P, Gao W, Liu J, Tian XY, Wong R, Zhou B, Lui KO*. (2026) METTL14 inhibits atherogenesis by epigenetically activating PPAR-α/γ transcription and fatty acid oxidation in VSMCs. Cardiovascular Research122:1001-1021.
- Hou Y, Ho CK, Lai B, Liu J, Li L, Lin J, Qu H, Wong RHL, Nie Y, Ding Q, Zhou B, Lui KO*. (2025) CD4+ Tregs regulate heart growth and regeneration through MRG15/TIP60-mediated epigenomic remodeling in proliferating cardiomyocytes. Circulation. 152:1634-1656
- Ye W, Gao W, Ho CK, Cui L, Lau JYW, Tian XY, Zhou B, Lui KO*. (2025) YY1 regulates vascular resistance and blood pressure dynamics through epigenetic control of m6A RNA modifications in VSMCs. Cardiovascular Research. 121:1898-1916.
- Liu D, Yang KY, Chan VW, Ye W, Chong CCN, Wang CC, Wang H, Zhou B, Cheng KKY, Lui KO*. (2022) YY1 regulates glucose homeostasis through controlling insulin transcription in pancreatic beta cells. Diabetes. 71:961-977
- Zhang S, Li Y, Huang X, Liu K, Wang QD, Chen AF, Sun K*, Lui KO*, Zhou B*. (2021) Seamless genetic recording of transiently activated mesenchymal gene expression in endothelial cells during cardiac fibrosis. Circulation. 144:2004-2020
- Li J, Li X, Liang C, Ling J, Chen Z, Wong CK, Waldmann H, Lui KO*. (2020) Coreceptor blockade targeting CD4 and CD8 allows acceptance of allogeneic human pluripotent stem cell grafts in humanized mice. Biomaterials. 248: 120013.
- Liang C, Yang KY, Chan VW, Li X, Fung THW, Wu Y, Tian XY, Huang Y, Qin L, Lau JYW, Lui KO*. (2020) CD8+ T-cell plasticity regulates vascular regeneration in type-2 diabetes. Theranostics10: 4217-4232.
- Li J, Yang KY, Tam RCY, Chan VW, Lan HY, Hori S, Zhou B, Lui KO*. (2019) Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. Theranostics. 9: 4324-4341.
- Leung CS, Yang KY, Li X, Chan VW, Ku M, Waldmann H, Hori S, Tsang JCH, Lo YMD, Lui KO*. (2018) Single-cell transcriptomics reveal that PD-1 mediates immune tolerance by regulating proliferation of regulatory T-cells. Genome Medicine. 10: 71.