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Professor NG Siew Chien

Professor NG Siew Chien

Assistant Dean (Development)

Croucher Professor in Medical Sciences

Professor, Department of Medicine and Therapeutics

CUHK Employment
  • Assistant Dean (Development), Faculty of Medicine
  • Professor, Department of Medicine and Therapeutics
  • Director, Microbiota I-Center (MagIC)
  • Associate Director, Centre for Gut Microbiota Research

  • Inflammatory Bowel Disease
  • Fecal Microbiota Transplantation
  • Colorectal Cancer
  • Endoscopy
  • Gut Microbiome


Education & Qualifications

MBBS (Lond), PhD (Lond), FRCP (Lond), FRCP (Edin), FHKCP, FHKAM (Medicine), AGAF



Research Interests
  • Epidemiology, genetics, pathogenesis, and treatment of IBD 
  • Role of Gut microbiota in health and disease
  • Fecal microbiota transplantation and microbial therapeutics

Additional Information


Award & Honour

  • New Cornerstone Investigator, 2023
  • High Flyer Innopreneur Award, Federation of Hong Kong Industries, 2023
  • Highly Cited Researchers by Clarivate in 2020, 2021, 2022 and 2023
  • Higher Education Outstanding Scientific Research Output Award – First-class Award in Natural Sciences, Ministry of Education, 2020
  • Joanna and David Sachar International Award and Visiting Professorship in IBD, Icahn School of Medicine, Mount Sinai, 2019
  • Sir Francis Avery Jones Visiting Professorship and Award, St Mark’s Hospital, London, 2019
  • Visiting Professor, Shanghai Medical College, Fudan University, China
  • Sir David Todd Lectureship, Hong Kong College of Physicians, 2017
  • Outstanding Fellow, Faculty of Medicine, The Chinese University of Hong Kong, 2017
  • Young Investigator Award, American Gastroenterology Association, 2016
  • Distinguished Research Paper Award for Young Investigators, Hong Kong College of Physicians in 2014, 2015 and 2016
  • Exemplary Teaching Award, Faculty of Medicine, The Chinese University of Hong Kong in 2014, 2015 and 2016
  • JGH Emerging Leader Lectureship Award, Asian-Pacific Association of Gastroenterology, 2014


Professional Service

  • Associate Editor, Gut
  • External Assessor, University of Malaya


Academic Engagement in CUHK

  • Mentor, MBChB Programme Global Physician-Leadership Stream (GPS)


Selected Publications
  1. SC Ng, Y Peng, L Zhang, CK Mok, S Zhao, A Li, JY Ching, Y Liu, S Yan, DLS Chan, J Zhu, C Chen, AC Fung, KK Wong, DS Hui, FK Chan, and HM Tun, Gut Microbiota Composition Is Associated with Sars-Cov-2 Vaccine Immunogenicity and Adverse Events. 02, 2022. Gut  
  2. Y Wan, T Zuo, Z Xu, F Zhang, H Zhan, D Chan, TF Leung, YK Yeoh, FKL Chan, R Chan, and SC Ng, Underdevelopment of the Gut Microbiota and Bacteria Species as Non-Invasive Markers of Prediction in Children with Autism Spectrum Disorder. 07, 2021. Gut
  3. YK Yeoh, T Zuo, GCY Lui, F Zhang, Q Liu, AYL Li, ACK Chung, CP Cheung, EYK Tso, KSC Fung, V Chan, L Ling, G Joynt, DSC Hui, KM Chow, SSS Ng, TCM Li, RWY Ng, TCF Yip, GLH Wong, FKL Chan, CK Wong, PKS Chan, and SC Ng, Gut Microbiota Composition Reflects Disease Severity and Dysfunctional Immune Responses in Patients with Covid-19. 04, 2021. Gut 70(4): p. 698-706
  4. SC Ng, ZL Xu, JWY Mak, KL Yang, Q Liu, T Zuo, W Tang, L Lau, RN Lui, SH Wong, YK Tse, AYL Li, K Cheung, JYL Ching, VWS Wong, APS Kong, RCW Ma, EYK Chow, SKH Wong, ICH Ho, PKS Chan, and FKL Chan, Microbiota Engraftment after Faecal Microbiota Transplantation in Obese Subjects with Type 2 Diabetes: A 24-Week, Double-Blind, Randomised Controlled Trial. 03, 2021. Gut p. 8
  5. F Zhang, T Zuo, YK Yeoh, FWT Cheng, Q Liu, W Tang, KCY Cheung, KL Yang, CP Cheung, CC Mo, MM Hui, FKL Chan, CK Li, PKS Chan, and SC Ng, Longitudinal Dynamics of Gut Bacteriome, Mycobiome and Virome after Fecal Microbiota Transplantation in Graft-Versus-Host Disease. 01, 2021. Nature Communications 12(1): p. 11
  6. T Zuo, F Zhang, GCY Lui, YK Yeoh, AYL Li, H Zhan, Y Wan, A Chung, CP Cheung, N Chen, CKC Lai, Z Chen, EYK Tso, KSC Fung, V Chan, L Ling, G Joynt, DSC Hui, FKL Chan, PKS Chan, and SC Ng, Alterations in Gut Microbiota of Patients with Covid-19 During Time of Hospitalization. 05, 2020. Gastroenterology
  7. SC Ng, MA Kamm, YK Yeoh, PKS Chan, T Zuo, W Tang, A Sood, A Andoh, N Ohmiya, Y Zhou, CJ Ooi, V Mahachai, CY Wu, F Zhang, K Sugano, and FKL Chan, Scientific Frontiers in Faecal Microbiota Transplantation: Joint Document of Asia-Pacific Association of Gastroenterology (Apage) and Asia-Pacific Society for Digestive Endoscopy (Apsde). 01, 2020. Gut 69(1): p. 83-91
  8. T Zuo, MA Kamm, JF Colombel, and SC Ng, Urbanization and the Gut Microbiota in Health and Inflammatory Bowel Disease. 07, 2018. Nature Reviews Gastroenterology & Hepatology 15(7): p. 440-452
  9. SC Ng, HY Shi, N Hamidi, FE Underwood, W Tang, EI Benchimol, R Panaccione, S Ghosh, JCY Wu, FKL Chan, JJY Sung, and GG Kaplan, Worldwide Incidence and Prevalence of Inflammatory Bowel Disease in the 21st Century: A Systematic Review of Population-Based Studies. 12, 2017. Lancet 390(10114): p. 2769-2778
  10. SC Ng, W Tang, JY Ching, M Wong, CM Chow, AJ Hui, TC Wong, VK Leung, SW Tsang, HH Yu, MF Li, KK Ng, MA Kamm, C Studd, S Bell, R Leong, HJ De Silva, A Kasturiratne, MNF Mufeena, KL Ling, CJ Ooi, PS Tan, D Ong, KL Goh, I Hilmi, P Pisespongsa, S Manatsathit, R Rerknimitr, S Aniwan, YF Wang, Q Ouyang, Z Zeng, Z Zhu, MH Chen, PJ Hu, K Wu, X Wang, M Simadibrata, M Abdullah, JC Wu, JJY Sung, and FKL Chan, Incidence and Phenotype of Inflammatory Bowel Disease Based on Results from the Asia-Pacific Crohn's and Colitis Epidemiology Study. 07, 2013. Gastroenterology 145(1): p. 158-165 e2