Professor NG Siew Chien
Associate Dean (Research)
Croucher Professor in Medical Sciences
Professor, Department of Medicine and Therapeutics
CUHK Employment
- Associate Dean (Research), Faculty of Medicine
- Professor, Department of Medicine and Therapeutics
- Director, Microbiota I-Center (MagIC)
- Associate Director, Centre for Gut Microbiota Research
- New Cornerstone Investigator
Expertise
- Inflammatory Bowel Disease
- Fecal Microbiota Transplantation
- Colorectal Cancer
- Endoscopy
- Gut Microbiome
Education & Qualifications
MBBS (Lond), PhD (Lond), FRCP (Lond), FRCP (Edin), AGAF, FHKCP, FHKAM (Medicine)
Research Interests
- Epidemiology, genetics, pathogenesis, and treatment of IBD
- Role of Gut microbiota in health and disease
- Fecal microbiota transplantation and microbial therapeutics
Additional Information
Award & Honour
Highly Cited Researchers by Clarivate in 2020 - 2025
Best Innopreneur Award 2025, Federation of Hong Kong Industries,
Bank of China Hong Kong Science and Technology Prize (Life and Health), Bank of China Hong Kong, 2024
Foreign Member of Academia Europaea (Clinical & Veterinary Science Section), Academia Europaea, 2024
The Visionary Women Awards 2024, Harper’s BAZAAR Hong Kong
New Cornerstone Investigator (Biological and Biomedical Sciences), New Cornerstone Science Foundation, 2023
Deloitte Technology Fast Outstanding Female Entrepreneur Award, Deloitte Hong Kong, 2023
High Flyer Innopreneur Award, Federation of Hong Kong Industries, 2023
Higher Education Outstanding Scientific Research Output Award – First-class Award in Natural Sciences, Ministry of Education, 2020
Joanna and David Sachar International Award and Visiting Professorship in IBD, Icahn School of Medicine, Mount Sinai, 2019
Sir Francis Avery Jones Visiting Professorship and Award, St Mark’s Hospital, London, 2019
Visiting Professor, Shanghai Medical College, Fudan University, China
Sir David Todd Lectureship, Hong Kong College of Physicians, 2017
Outstanding Fellow, Faculty of Medicine, The Chinese University of Hong Kong, 2017
Exemplary Teaching Award, Faculty of Medicine, The Chinese University of Hong Kong in 2014, 2015 and 2016
Professional Service
- President, The Hong Kong Society of Gastroenterology
- Associate Editor, Gut
- Advisory Board, Cell Host & Microbe
- Board Member, Cell Genomics
- External Assessor, University of Malaya
- External Assessor, University of New South Wales
Selected Publications
- L Hracs, JW Windsor, J Gorospe, M Cummings, S Coward, MJ Buie, J Quan, Q Goddard, L Caplan, A Markovinović, T Williamson, Y Abbey, M Abdullah, MT Abreu, V Ahuja, RA Raja Ali, M Altuwaijri, D Balderramo, R Banerjee, EI Benchimol, CN Bernstein, E Brunet-Mas, J Burisch, VH Chong, I Dotan, U Dutta, S El Ouali, A Forbes, A Forss, R Gearry, VH Dao, JL Hartono, I Hilmi, P Hodges, GR Jones, F Juliao-Baños, J Kaibullayeva, P Kelly, T Kobayashi, PG Kotze, PL Lakatos, CW Lees, J Limsrivilai, B Lo, EV Loftus, Jr., JF Ludvigsson, JWY Mak, Y Miao, KK Ng, S Okabayashi, O Olén, R Panaccione, MS Paudel, AB Quaresma, DT Rubin, M Simadibrata, Y Sun, H Suzuki, M Toro, D Turner, B Iade, SC Wei, JK Yamamoto-Furusho, SK Yang, SC Ng, and GG Kaplan, Global Evolution of Inflammatory Bowel Disease across Epidemiologic Stages. 04, 2025.Nature 642: p. 458-466
- J Zheng, Q Sun, M Zhang, C Liu, Q Su, L Zhang, Z Xu, W Lu, J Ching, W Tang, CP Cheung, AL Hamilton, AL Wilson O'Brien, SC Wei, CN Bernstein, DT Rubin, EB Chang, M Morrison, MA Kamm, FKL Chan, J Zhang, and SC Ng, Noninvasive, Microbiome-Based Diagnosis of Inflammatory Bowel Disease. 12, 2024.Nature Medicine 30: p. 3555-3567
- Q Su, OWH Wong, WQ Lu, YT Wan, L Zhang, WY Xu, MKT Li, CY Liu, CP Cheung, JYL Ching, PK Cheong, TF Leung, SD Chan, P Leung, FKL Chan, and SC Ng, Multikingdom and Functional Gut Microbiota Markers for Autism Spectrum Disorder. 07, 2024.Nature Microbiology 9: p. 2344-2355
- Q Su, RI Lau, Q Liu, MKT Li, JW Yan Mak, W Lu, ISF Lau, LHS Lau, GTY Yeung, CP Cheung, W Tang, C Liu, JYL Ching, PK Cheong, FKL Chan, and SC Ng, The Gut Microbiome Associates with Phenotypic Manifestations of Post-Acute Covid-19 Syndrome. 05, 2024.Cell Host & Microbe 32(5): p. 651-660.e4
- RI Lau, Q Su, ISF Lau, JYL Ching, MCS Wong, LHS Lau, HM Tun, CKP Mok, SWH Chau, YK Tse, CP Cheung, MKT Li, GTY Yeung, PK Cheong, FKL Chan, and SC Ng, A Synbiotic Preparation (Sim01) for Post-Acute Covid-19 Syndrome in Hong Kong (Recovery): A Randomised, Double-Blind, Placebo-Controlled Trial. 03, 2024.Lancet Infectious Diseases 24(3): p. 256-265
- Q Su, Q Liu, RI Lau, JW Zhang, ZL Xu, YK Yeoh, TWH Leung, W Tang, L Zhang, JQY Liang, YK Yau, JY Zheng, CY Liu, MJ Zhang, CP Cheung, JYL Ching, HM Tun, J Yu, FKL Chan, and SC Ng, Faecal Microbiome-Based Machine Learning for Multi-Class Disease Diagnosis. 11, 2022.Nature Communications 13(1)
- RI Lau, F Zhang, Q Liu, Q Su, FKL Chan, and SC Ng, Gut Microbiota in Covid-19: Key Microbial Changes, Potential Mechanisms and Clinical Applications. 10, 2022.Nature Reviews Gastroenterology & Hepatology 20: p. 323-337
- J Zhang, EC Hoedt, Q Liu, E Berendsen, JJ Teh, A Hamilton, OB AW, JYL Ching, H Wei, K Yang, Z Xu, SH Wong, JWY Mak, JJY Sung, M Morrison, J Yu, MA Kamm, and SC Ng, Elucidation of Proteus Mirabilis as a Key Bacterium in Crohn's Disease Inflammation. 01, 2021.Gastroenterology 160(1): p. 317-330.e11
- SC Ng, HY Shi, N Hamidi, FE Underwood, W Tang, EI Benchimol, R Panaccione, S Ghosh, JCY Wu, FKL Chan, JJY Sung, and GG Kaplan, Worldwide Incidence and Prevalence of Inflammatory Bowel Disease in the 21st Century: A Systematic Review of Population-Based Studies. 12, 2017.Lancet 390(10114): p. 2769-2778
- SC Ng, W Tang, RW Leong, M Chen, Y Ko, C Studd, O Niewiadomski, S Bell, MA Kamm, HJ De Silva, A Kasturiratne, YU Senanayake, CJ Ooi, KL Ling, D Ong, KL Goh, I Hilmi, Q Ouyang, YF Wang, P Hu, Z Zhu, Z Zeng, K Wu, X Wang, B Xia, J Li, P Pisespongsa, S Manatsathit, S Aniwan, M Simadibrata, M Abdullah, SWC Tsang, TC Wong, AJ Hui, CM Chow, HH Yu, MF Li, KK Ng, J Ching, JCY Wu, FKL Chan, and JJY Sung, Environmental Risk Factors in Inflammatory Bowel Disease: A Population-Based Case-Control Study in Asia-Pacific. 07, 2015.Gut 64(7): p. 1063-1071