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助理院長 (研究)


  • 醫學院助理院長 (研究)
  • 內科及藥物治療學系及生物醫學學院助理教授
  • 精神科學系名譽助理教授
  • 張金菱治療柏金遜綜合症研究中心副主任
  • 李嘉誠健康科學研究所首席研究員 

  • 蔡永業腦神經科學中心首席研究員


  • 神經科學






  • 神經退化疾病中的膠質與血管細胞異常
  • 神經迴路
  • 成像技術開發




  • 裘槎前瞻科研大獎, 2020
  • Finalist, Eppendorf 與 Science 神經生物學獎, 2014
部分論文 (只有英文版本)

Researcher ID:


  1. Zhao L, Li Z, Vong JSL, Chen X, Lai HM, Yan LYC, Huang J, Sy SKH, Tian X, Huang Y, Chan HYE, So HC, Ng WL, Tang Y, Lin WJ, Mok VCT, Ko H. Pharmacologically reversible zonation-dependent endothelial cell transcriptomic changes with neurodegenerative disease associations in the aged brain. Nature Communications. 2020 Sep 4;11(1):4413.
  2. Ko H, Lam BYK, Mok VCT. Pathophysiology of vascular cognitive impairment (II): amyloid contribution in vascular cognitive impairment. Invited book chapter in Stroke Revisited: Vascular Cognitive Impairment. Springer Press. 2020 ISBN 978-981-10-1433-8.
  3. Li Q, Ko H (co-1st author), Qian ZM, Yan LYC, Chan DCW, Arbuthnott GW, Ke Y, Yung WH. Refinement of learned skilled movement representation in motor cortex deep output layer. Nature Communications. 2017 Jun 9;8:15834.
  4. Okun M, Steinmetz N, Cossell L, Iacaruso MF, Ko H, Bartho P, Moore T, Hofer SB, Mrsic-Flogel TD, Carandini M, Harris KD. Diverse coupling of neurons to populations in sensory cortex. Nature. 2015 May 28;521(7553):511-5.
  5. Cossell L, Iacaruso MF, Muir DR, Houlton R, Sader EN, Ko H, Hofer SB, Mrsic-Flogel TD. Functional organization of excitatory synaptic strength in primary visual cortex. Nature. 2015 Feb 19;518(7539):399-403.
  6. Ko H. Functional organization of synaptic connectivity in the neocortex. Runner-up, Eppendorf and Science Prize for Neurobiology 2014. Science. 2014 Oct 31; 346(6209):555.
  7. Ko H, Mrsic-Flogel TD, Hofer SB. Emergence of feature-specific connectivity in cortical microcircuits in the absence of visual experience. The Journal of Neuroscience. 2014 Jul 16;34(29):9812-6.
  8. Ko H, Cossell L, Baragli C, Antolik J, Clopath C, Hofer SB, Mrsic-Flogel TD. The emergence of functional microcircuits in visual cortex. Nature. 2013 Apr 4;496(7443):96-100.
  9. Hofer SB, Ko H(co-1st author), Pichler B, Vogelstein J, Ros H, Zeng H, Lein E, Lesica NA, Mrsic-Flogel TD. Differential connectivity and response dynamics of excitatory and inhibitory neurons in visual cortex. Nature Neuroscience. 2011 Jul 17;14(8):1045-52.
  10. Ko H, Hofer SB, Pichler B, Buchanan KA, Sjostrom PJ, Mrsic-Flogel TD. Functional specificity of local synaptic connections in neocortical networks. Nature. 2011 May 5;473(7345):87-91.