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Professor LEUNG Tak Yeung

Professor LEUNG Tak Yeung

Assistant Dean (Mainland Affairs)

Professor, Department of Obstetrics and Gynaecology

CUHK Employment
  • Assistant Dean (Mainland Affairs), Faculty of Medicine

  • Professor, Department of Obstetrics and Gynaecology


  • Fetal therapy including fetoscopic laser therapy for Twin-twin transfusion syndrome, radiofrequency ablation of umbilical vessels for selective feticide or fetal reduction, fetoscopic endotracheal balloon occlusion (FETO) for congenital diaphragmatic hernia,  in utero transfusion and shunting
  • Genetic screening, diagnosis and counselling with state-of-art technologies including ultrasonography, chromosomal microarray, non-invasive prenatal testing (NIPT) using maternal circulating cell-free fetal DNA, and next generation sequencing
  • External cephalic version for breech presentation


Education & Qualifications

MBChB (CUHK), MD (CUHK), FHKCOG, FHKAM (Obstetrics and Gynaecology), FRCOG


Research Interests
  • Prenatal genetic screening and diagnosis and therapy of fetal abnormalities,
  • Twin pregnancy
  • Preterm delivery
  • Fetal growth restriction
  • External cephalic version


Additional Information

Professional Service

  • President, Hong Kong College of Obstetricians & Gynaecologists
  • Scientific Editor, British Journal of Obstetrics and Gynaecology

Selected Publications


  1. Dong Z, Wang H, Chen H, Jiang H, Yuan J, Yang Z, Wang WJ, Xu F, Guo X, Cao Y, Zhu Z, Geng C, Cheung WC, Kwok YK, Yang H, Leung TY, Morton CC, Cheung SW, Choy KW. Identification of balanced chromosomal rearrangements previously unknown among participants in the 1000 Genomes Project: implications for interpretation of structural variation in genomes and the future of clinical cytogenetics Genet Med in press
  2. Cheng YKY, Leung TY, Law LW, Ting YH, Law KM, Sahota DS. First trimester screening for pre-eclampsia in Chinese pregnancies: Case control study. BJOG 2018 Mar;125(4):442-449.
  3. Khaw KS, Lee SW, Ngan Kee WD, Law LW, Lau TK, Ng FF, Leung TY. Randomized trial of anaesthetic interventions in external cephalic version for breech presentation. Br J Anaesth. 2015 Jun;114(6):944-50.
  4. Hui SY, Chor CM, Lau TK, Lao TT, Leung TY. Cerclage Pessary for Preventing Preterm Birth in Women with a Singleton Pregnancy and a Short Cervix at 20 to 24 Weeks: A Randomized Controlled Trial. Am J Perinatol 2013; 30:283-8.
  5. Leung TY, Qu JZ, Liao GJ, Jiang P, Cheng YK, Chan KC, Chiu RW, Lo YM. Noninvasive twin zygosity assessment and aneuploidy detection by maternal plasma DNA sequencing. Prenat Diagn 2013; 33:675-81.
  6. Leung TY, Vogel I, Lau TK, Chong W, Hyett JA, Petersen OB, Choy KW. Identification of submicroscopic chromosomal aberrations in fetuses with increased nuchal translucency and an apparently normal karyotype. Ultrasound Obstet Gynecol 2011; 38: 314-319.
  7. Leung TY, Stuart O, Sahota DS, Suen SS, Lau TK, Lao TT. Head-to-body delivery interval and risk of fetal acidosis and hypoxic ischaemic encephalopathy in shoulder dystocia: a retrospective review. BJOG 2011; 118:474-479.
  8. Leung TY, Chung PW, Rogers MS, Sahota DS, Lao TT, Chung TK. Urgent Cesarean delivery for fetal bradycardia. Obstet Gynecol2009; 114: 1023-1028.
  9. Leung TY, Leung TN, Sahota DS, Chan OK, Chan LW, Fung TY, Lau TK. Obesity. Trends in maternal obesity and associated risks of adverse pregnancy outcomes in a population of Chinese women. BJOG 2008; 115: 1529-1537.
  10. Chiu RW, Chan KC, Gao Y, Lau VY, Zheng W, Leung TY , Foo CH, Xie B, Tsui NB, Lun FM, Zee BC, Lau TK, Cantor CR, Lo YM. Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma. Proc Natl Acad Sci USA 2008; 105: 20458-20463.