Professor QIN Ling
Assistant Dean (Mainland Affairs)
Choh-Ming Li Professor of Orthopaedics and Traumatology
CUHK Employment
- Assistant Dean (Mainland Affairs), Faculty of Medicine
- Choh-Ming Li Professor of Orthopaedics and Traumatology
- Director, CUHK Hong Kong-Shenzhen Innovation and Technology Research Institute
- Director, Innovative Orthopaedic Biomaterials and Drug Translational Research Laboratory, Li Ka Shing Institute of Health Sciences
- Director, Musculoskeletal Research Laboratory
Expertise
- Advanced Diagnosis, Prevention and Treatment of Bone Metabolic Disorders, especially Osteoporosis and Osteonecrosis, and Healing Enhancement of Musculoskeletal Injuries, in Collaboration with Research and Clinical Scientists in Medicine, Geriatrics, Rheumatologists, Traditional Medicine, and Biomaterials
- Musculoskeletal Imaging, especially in Bone Densitometry, Histomorphometry and Skeletal Biomechanics
Education & Qualifications
BEd, MEd (Beijing Inst. of Phy. Ed.); PhD (German Sports Univ. Cologne); MIBMS, MSIROT, MASBMR, FBSE
Research Interests
Musculoskeletal Disorders, including Osteoporosis, Osteonecrosis and Osteoarthritis
- Musculoskeletal Injury and Repair, including Fracture and Tendon-Bone Insertion Repair
Additional Information
Award & Honour
- Collage fellow of American Institute of Medical and Biological Engineering
- Collage fellow of International Combined Orthopaedic Research Societies
- Fellow of American Society of Bone and Mineral Research
- Fellow of International Union of Sciences for Biomaterials Science and Engineering
Professional Service
- Past President of the International Chinese Musculoskeletal Research Society (ICMRS)
- Editor-in-chief of Journal of Orthopaedic Translation
- Associate Editor of Clinical Biomechanics and Chinese Journal of Orthopaedic Surgery
- Board member of International Journal of Sports Medicine
Selected Publications
- Tong WX, Zeng YL, Chow HK, Yeung W, Xu JK, Deng YJ, Chen SH, Zhao H, Zhang XL, Ho KW, QinL*, Mak KL*. Wnt16 attenuates osteoarthritis progression through a PCP/JNK-mTORC1-PTHrP cascade. Annals of the Rheumatic Diseases, 78:551-561, 2019
- Feng Q, Xu JK, Zhang KY, Yao H, Zheng NY, Zheng LZ, Wang JL, Wei KC, Xiao XF, Qin L*, Bian LM* Dynamic and cell-infiltratable hydrogels as injectable carrier of therapeutic cells and drugs for treating challenging bone defects. ACS Central Science, 5:440-450, 2019
- Huang L, Wang XL, Cao HJ, Li L, Chow HW, Tian L, Wu H, Zhang JY, Wang N, Zheng LZ, Yao XS, Yang ZJ*, Qin L*. A bone-targeting delivery system carrying osteogenic phytomolecule icaritin prevents osteoporosis in mice. Biomaterials, 182:58-72, 2018
- Wang JL, Wu YH, Li HF, Liu Y, Bai XL, Chau WH, Zheng YF*, Qin L*. Magnesium Alloy based Interference Screw Developed for ACL Reconstruction Attenuates Peri-Tunnel Bone Loss in Rabbits. Biomaterials,11;157:86-97, 2018
- Wang J, Xu J, Song B, Chow DH, Shu-Hang Yung P, Qin L*. Magnesium (Mg) based interference screws developed for promoting tendon graft incorporation in bone tunnel in rabbits. Acta Biomaterialia 63:393-410, 2017
- Zhang Y, Xu J, Ruan YC, Yu MK, O'Laughlin M, Wise H, Chen D, Tian L, Shi D, Wang J, Chen S, Feng JQ, Chow DH, Xie X, Zheng L, Huang L, Huang S, Leung K, Lu N, Zhao L, Li H, Zhao D, Guo X, Chan K, Witte F, Chan HC, Zheng Y, Qin L*. Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats. Nature Medicine, 22(10):1160-1169, 2016
- Zheng LZ, Cao HJ, Chen SH, Tang T, Fu WM, Huang L, Chow DH, Wang YX, Griffith JF, He W, Zhou H, Zhao DW, Zhang G, Wang XL, Qin L*. Blockage of Src by Specific siRNA as a novel therapeutic strategy to prevent destructive repair in steroid-associated osteonecrosis in Rabbits. J Bone Miner Res 30(11):2044-57, 2015
- Wang JL, Witte F, Xi TF, Zhang YF, Yang K, Yang YS, Zhao DW, Meng J, Li YD, Li WR, Chan KM, Qin L*. Recommendation for modifying current cytotoxicity testing standards for biodegradable magnesium-based materials. Acta Biomaterialia 21:237-49, 2015
- Qin L*, Yao D, Zheng LZ, Liu WC, Liu Z, Lei M, Huang L, Xie XH, Wang XL, Chen Y, Yao XS, Peng J, Gong H, Griffith JF, Huang YP, Zheng YP, Feng JQ, Liu Y, Chen SH, Xiao DM, Wang DP, Xiong JY, Pei DQ, Zhang P, Pan XH, Wang XH, Lee KM, CY Cheng. Phytomolecule Icaritin incorporated PLGA/TCP scaffold for steroid-associated osteonecrosis: Proof-of-concept for prevention of hip joint collapse in bipedal emus and mechanistic study in quadrupedal rabbits. Biomaterials 59: 125-43, 2015
- Zhang G*, Guo BS, Wu H, Tang T, Zhang BT, Zheng LZ, He YX, Yang ZJ, Pan XH, Chow HL, To KW, Li YP, Li DH, Wang XL,Wang YX, Lee KM, Hou ZB, Dong N, Li G, Leung KS, Hung LK, He FC, Zhang LQ*, Qin L*. A delivery system targeting bone formation surface to facilitate RNAi-based bone anabolic therapy. Nature Medicine 18(2):307-14, 2012
*corresponding author