Professor WONG Lai Hung, Grace
Assistant Dean (Learning Experience)
Kuok Group Professor in Gastroenterology and Hepatology
Professor, Department of Medicine and Therapeutics
CUHK Employment
- Assistant Dean (Learning Experience), Faculty of Medicine
- Kuok Group Professor in Gastroenterology and Hepatology
- Division Head (Academic Affairs), Division of Gastroenterology and Hepatology, Department of Medicine and Therapeutics
- Professor, Institute of Digestive Disease
- Professor, State Key Laboratory of Digestive Diseases (CUHK)
Expertise
- Gastroenterology and Hepatology
- Hepatitis
- Liver Cancer
- Liver Fibrosis
- Peptic Ulcer
Education and Qualifications
MBChB (CUHK), MD (CUHK), FRCP (Lond, Edin), FHKCP, FHKAM (Medicine)
Research Interests
- Chronic Viral Hepatitis B and C
- Hepatocelluar Carcinoma
- Non-Invasive Assessment of Liver Fibrosis
- Idiopathic Peptic Ulcer
- Big Data In Medicine
Additional Information
Award & Honour
- Fellow of the American Association for the Study of Liver Diseases (AASLD), 2026
- Highly Cited Researcher (Clinical Medicine), Clarivate Analytics, 2025
- Highly Cited Researcher (Cross-Field), Clarivate Analytics, 2024
- Outstanding Project Team on COVID-19 Research Award, Health Bureau, 2024
- Highly Cited Researcher (Cross-Field), Clarivate Analytics, 2023
- Guangdong Province Science & Technology First Class Award, 2024
- Investigator Award Hong Kong College of Physicians
- Asian-Pacific Association for the Study of the Liver (APASL) 2024 Kyoto
- Best reviewer award, Journal of Hepatology 2022
- Richard Yu Lectureship, Hong Kong College of Physicians 2021
- Presidential Awards (Public Health), Global Hepatitis Summit 2021
- Presidential Plenary Award APASL, Manila, 2019
- Best Review Paper, Clinical and Molecular Hepatology Journal 2018
- Guangdong Province Science & Technology First Class Award, 2018
- JGHF Emerging Leader Lectureship, JGH Foundation, 2017
- Sir David Todd Lectureship, Hong Kong College of Physicians, 2016
- Distinguished Research Paper Award for Young Investigators, Hong Kong College of Physicians, 2010, 2013, 2014, 2015
- Ten Outstanding Young Persons Award, Hong Kong, 2014
- Travel Grant Award, School of Research Methodology, the 22nd Conference of the Asian-Pacific Association for the Study of the Liver, 2012
- Young Investigator Award: Asian Pacific Association for the Study of the Liver, Hong Kong, 2009
- Bronze Award, Best Original Research by Trainees: Hong Kong Academy of Medicine, 2008
Professional Service
- Convenor of Clinical Coordinating Committee (COC) Medicine/GI, Hospital Authority
- Associate Editor, Hepatology
- Panel member, APASL Clinical Practice Guidelines for Chronic Hepatitis B 2026
Academic Engagement in CUHK
Course Director, Master of Science Programme in Gastroenterology
Selected Publications
- Wong GL, Yuen MF, Lin B, et al. Elebsiran and PEG-IFNα for chronic hepatitis B infection: a partially randomized, open-label, phase 2 trial. Nat Med 2026;32:151-159.
- Wong GL, Gane E, Pan CQ, et al. Efficacy and Safety of Tenofovir Alafenamide (TAF) and Tenofovir Disoproxil Fumarate (TDF) Followed by TAF in Chronic Hepatitis B Patients of East Asian Ethnicity Following 5 Years of Treatment. Aliment Pharmacol Ther 2026;63:132-144.
- Wong GL, Lemoine M. The 2024 updated WHO guidelines for the prevention and management of chronic hepatitis B: Main changes and potential implications for the next major liver society clinical practice guidelines. J Hepatol 2025;82:918-925.
- Wong GL. Updated Guidelines for the Prevention and Management of Chronic Hepatitis B-World Health Organization 2024 Compared With China 2022 HBV Guidelines. J Viral Hepat 2024;31 Suppl 2:13-22.
- Wong GL, Yip TC, Lai MS, et al. Incidence of Viral Rebound After Treatment With Nirmatrelvir-Ritonavir and Molnupiravir. JAMA Netw Open 2022;5:e2245086.
- Wong GL, Hui VW, Yip TC, et al. Minimal risk of drug-induced liver injury with molnupiravir and ritonavir-boosted nirmatrelvir. Gastroenterology 2023;164:151-153.
- Wong GL, Ong JP, Kaewdech A, Su TH. Halfway through HBV elimination - are we not waiting? Int J Infect Dis. 2023;134:299-300.
- Wong GL, Gane E, Lok ASF. How to achieve functional cure of HBV: Stopping NUCs, adding interferon or new drug development? J Hepatol 2022;76:1249-1262.
- Wong GL, Hui VW, Tan Q, et al. Novel machine learning models outperform risk scores in predicting hepatocellular carcinoma in patients with chronic viral hepatitis. JHEP Rep 2022;4:100441. doi: 10.1016/j.jhepr.2022.100441. eCollection 2022 Mar.
- Wong GL, Wong VW, Hui VW, et al. Hepatitis Flare During Immunotherapy in Patients With Current or Past Hepatitis B Virus Infection. Am J Gastroenterol 2021;116:1274-1283.