A risk score to identify potential colorectal cancer
It is essential to determine the need for subsequent colonoscopy follow-up evaluation after flexible sigmoidoscopy screening. Although there are some prediction models of advanced proximal neoplasia (APN) in Western countries, they were found to be limited in Asian population. In the analysis “Development and Validation of the Asia-Pacific Proximal Colon Neoplasia Risk Score”, a scoring system to identify people at risk for APN was developed and validated from 14 Asia-Pacific study sites. This score consisted of age, smoking habits, colorectal cancer family history and the presence of neoplasia in the distal colorectum. Screening candidates with a score of 4 or above should be referred for colonoscopy examination. (Clin Gastroenterol Hepatol. 2020 Jan 7. pii: S1542-3565(20)30004-5. doi: 10.1016/j.cgh.2019.12.031. [Epub ahead of print])
Anyone interested in future collaboration in this field of research is welcome to contact our key investigator Prof. Joseph SUNG in the Department of Medicine and Therapeutics, CUHK. Prof. Sung is the director of Institute of Digestive Disease. His research focuses on intestinal bleeding, helicobacter pylori, peptic ulcer, hepatitis B, colorectal cancer and other cancers related to the digestive system.
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