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Preeclampsia, a multisystem disorder of pregnancy, is one of the leading causes of maternal and perinatal morbidity and mortality. In the recent joint study, the team discovered that aspirin reduced the risk of preeclampsia by delaying the gestational age. They collected the plasma samples of women with and without preeclampsia and built a metabolic clock of gestation. Results showed that aspirin significantly decelerated metabolic gestational-age by 1.27 weeks in mid-gestation, suggesting that the use of aspirin may delay the onset of preeclampsia. (Hypertension. 2021 Jul 6;HYPERTENSIONAHA12117448. doi: 10.1161/HYPERTENSIONAHA.121.17448. Online ahead of print)


Anyone interested in future collaboration in this field of research is welcome to contact our key investigator Prof. Liona POON from the Department of Obstetrics and Gynaecology, CUHK. Prof. Poon’s research focuses on the prediction and prevention of maternal and perinatal morbidity and mortality. These include developing screening models for the prediction of aneuploidies, preeclampsia, fetal growth restriction, gestational diabetes, macrosomia, stillbirth, spontaneous preterm birth and induced labour.