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Cerebral perfusion in intracranial atherosclerotic stenosis




The study “Sustaining cerebral perfusion in intracranial atherosclerotic stenosis: The roles of antegrade residual flow and leptomeningeal collateral flow” looked at the transit time of blood flow in the middle cerebral artery of patients with symptomatic stenosis. Findings show that both antegrade residual flow and leptomeningeal collateral flow play important roles for patients with a symptomatic middle cerebral artery stenosis; however, cerebral perfusion is more significantly dependent on antegrade residual flow in patients with moderate stenoses and more significantly dependent on collateral flow in patients with severe stenoses (J Cereb Blood Flow Metab. 2018 Oct 23:271678X18805209. doi: 10.1177/0271678X18805209. [Epub ahead of print]).
Anyone interested in future collaboration in this field of research is welcome to contact our key investigator, Prof Thomas Leung of our Department of Neurology. Prof Leung is an international expert in stroke research, imaging and intervention. He set up the first 'Transient Ischemic Attack (TIA) Clinic' in Hong Kong and provided suggestions and plans for the national stroke guidelines and policy in China.
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