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The study of “Soluble CD163 and mannose receptor associate with chronic hepatitis B activity and fibrosis and decline with treatment” suggests that macrophages are key players in chronic hepatitis B related liver inflammation and subsequent fibrosis. Both soluble macrophage activation markers and mannose receptors decrease with anti-viral treatment (J Gastroenterol Hepatol. 2017 Jun 15. doi: 10.1111/jgh.13849. [Epub ahead of print]).
Anyone interested in future collaboration in this field of research is welcome to contact our key investigator Prof Henry Chan, Head of Division of Gastroenterology and Hepatology in our Department of Medicine and Therapeutics. Prof Chan is an expert in antiviral treatment of chronic hepatitis B and has led numerous global clinical trials in the development of antiviral therapies.
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