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Same liver stiffness measurement cut-offs for M and XL probes



Current guidelines recommend non-invasive tests of liver fibrosis as initial assessment of non-alcoholic fatty liver disease. The latest model of vibration-controlled transient elastography, a non-invasive test of fibrosis, automatically selects M or XL probe according to patients’ body mass index. Based on analysis of a large sample size of patients from both Europe and Asia, the study on “Unified interpretation of liver stiffness measurement by M and XL probes in non-alcoholic fatty liver disease” shows that clinicians may use the same liver stiffness measurement cut-offs for both probes and that adjustment for severe hepatic steatosis is unnecessary when XL probe is used in obese patients (Gut. 2019 Jan 18. pii: gutjnl-2018-317334. doi: 10.1136/gutjnl-2018-317334. [Epub ahead of print]).
Anyone interested in future collaboration in this field of research is welcome to contact our key investigator, Prof Vincent Wong of our Department of Medicine and Therapeutics. Prof Wong is an expert in non-alcoholic fatty liver disease with a particular interest in the non-invasive assessment and treatment of chronic liver diseases.
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