Search
What are you looking for?
Start main content

Press Releases

Press Releases

https://www.med.cuhk.edu.hk/press-releases/cuhk-pioneers-surgical-treatment-of-deep-brain-stimulation-for-tardive-dystonia-in-hk
https://www.med.cuhk.edu.hk/press-releases/cuhk-pioneers-surgical-treatment-of-deep-brain-stimulation-for-tardive-dystonia-in-hk

CUHK Pioneers Surgical Treatment of Deep Brain Stimulation for Tardive Dystonia in HK

Tardive Dystonia is a movement disorder caused by the use of neuroleptic medications and the subsequent hypersensitive response of dopamine receptors in the deep brain, with a latency of onset of days to years after exposure. The disorder affects all four limbs and the whole body of the patients, with the head and neck being the most common and severely affected areas. Patients will suffer constant muscle pain and disabling limbs twitching, and at its advanced stage, will suffer significant morbidities, such as fracture of the cervical spine and ribs, leading to a state of complete dependence in daily activities. Withdrawal of the offending neuroleptic medications and therapies relieving muscle clamp are the traditional treatment methods. However, the remission rate is low once it is developed. 

 

(from left) Dr Koi Man CHENG, Associate Consultant, Castle Peak Hospital; Dr Xian Lun ZHU, Clinical Associate Professor (honorary), Division of Neurosurgery, CUHK; Professor Wai Sang POON, Head of Division of Neurosurgery, CUHK; Dr Danny Tat Ming CHAN, Clinical Assistant Professor (honorary), Division of Neurosurgery, CUHK and Professor Yun Kwok WING, Professor, Department of Psychiatry, CUHK

(from left) Dr Koi Man CHENG, Associate Consultant, Castle Peak Hospital; Dr Xian Lun ZHU, Clinical Associate Professor (honorary), Division of Neurosurgery, CUHK; Professor Wai Sang POON, Head of Division of Neurosurgery, CUHK; Dr Danny Tat Ming CHAN, Clinical Assistant Professor (honorary), Division of Neurosurgery, CUHK and Professor Yun Kwok WING, Professor, Department of Psychiatry, CUHK.

Surgical treatment by Deep Brain Stimulation (DBS) was reported effective in relieving the symptoms. In the surgery, two electrodes (each with a diameter of 1.2mm) are inserted bilaterally into the Globus pallidus of the deep brain with the stereotactic technique. Continuous electrical stimulation is delivered to the Globus pallidus through a pacemaker implanted in the chest wall. 

 

In December 2004, the Movement Disorder Group composed of medical professionals from Division of Neurosurgery, Department of Surgery and Division of Neurology, Department of Medicine and Therapeutics at The Chinese University of Hong Kong (CUHK) performed the first successful DBS surgery in Hong Kong. So far, a total of three patients (one man and two women; age 28-49 years old) with Tardive Dystonia had such surgery. All three patients suffered from severe pain and disabling dystonia a few years after exposure to neuroleptic medications. They were referred to the Prince of Wales Hospital by psychiatrists at Castle Peak Hospital. Two of them became bedridden and needed tube feeding before DBS. They all showed dramatic improvement after DBS. Both dystonia and pain were relieved. They could get out of bed and walk independently four days after the surgery; the swallowing problem and risk of aspiration resolved in six weeks; and they were able to return home and the community within three months.

More Press Releases

CUHK Introduces High Frequency Oscillations to Determine Resection Margin Increases the Effectiveness of Complex Epilepsy Surgery by around 30%

CUHK Introduces High Frequency Oscillations to Determine Resection Margin Increases the Effectiveness of Complex Epilepsy Surgery by around 30%

Surgical advancement
CU Medicine identifies the road map of emergence of circadian dysfunction and psychopathologies in the offspring of parents with bipolar disorder in the Greater Bay Area

CU Medicine identifies the road map of emergence of circadian dysfunction and psychopathologies in the offspring of parents with bipolar disorder in the Greater Bay Area

Research
CU Medicine-developed app proves effective in assessing depression

CU Medicine-developed app proves effective in assessing depression

Research
CUHK launches the Jockey Club Sleep Well Project –  Hong Kong’s first large-scale community outreach programme to promote sleep health, using cognitive behavioural therapy to treat insomnia

CUHK launches the Jockey Club Sleep Well Project – Hong Kong’s first large-scale community outreach programme to promote sleep health, using cognitive behavioural therapy to treat insomnia

Health Campaign
CUHK confirms depression sufferers with rapid eye movement sleep behaviour disorder harbour familial predisposition to neurodegeneration Provides new insights on improving precision psychiatry and preventing neurodegeneration

CUHK confirms depression sufferers with rapid eye movement sleep behaviour disorder harbour familial predisposition to neurodegeneration Provides new insights on improving precision psychiatry and preventing neurodegeneration

Research
CUHK discovers the occurrence of gut microbiome dysbiosis at the prodromal stages of Parkinson’s disease Gives novel insights into neurodegenerative prevention, intervention and diagnosis

CUHK discovers the occurrence of gut microbiome dysbiosis at the prodromal stages of Parkinson’s disease Gives novel insights into neurodegenerative prevention, intervention and diagnosis

Research
CU Medicine and International Surgeons Suggest Patients with Positive COVID-19 Results Should Delay Surgery for Seven Weeks to Reduce Death Risk

CU Medicine and International Surgeons Suggest Patients with Positive COVID-19 Results Should Delay Surgery for Seven Weeks to Reduce Death Risk

International collaboration
CUHK-HKU-UL Conducts World’s First Insomnia Prevention Programme and Proves Insomnia is Preventable in At-risk Adolescents

CUHK-HKU-UL Conducts World’s First Insomnia Prevention Programme and Proves Insomnia is Preventable in At-risk Adolescents

Research
CUHK-HKU Study Proves Bright Light Therapy as an Adjunctive Treatment Improves Outcomes in Depressed “Night Owl” Patients

CUHK-HKU Study Proves Bright Light Therapy as an Adjunctive Treatment Improves Outcomes in Depressed “Night Owl” Patients

Research
CUHK Successfully Conducts Asia-Pacific’s First Hybrid Operating Room Non-invasive Bronchoscopic Microwave Ablation to Treat Lung Cancer

CUHK Successfully Conducts Asia-Pacific’s First Hybrid Operating Room Non-invasive Bronchoscopic Microwave Ablation to Treat Lung Cancer

Surgical advancement
CUHK Conducts World’s First Family Study on Rapid Eye Movement Sleep Behaviour Disorder to Investigate Familial Link with Parkinson’s Disease

CUHK Conducts World’s First Family Study on Rapid Eye Movement Sleep Behaviour Disorder to Investigate Familial Link with Parkinson’s Disease

Research
CUHK Deepening Ties with World Leading Institutes for Transdisciplinary Medical Robotics Research to Reshape the Future of Diagnosis and Treatment

CUHK Deepening Ties with World Leading Institutes for Transdisciplinary Medical Robotics Research to Reshape the Future of Diagnosis and Treatment

International collaboration
CUHK Successfully Conducted the World’s First Multi-Specialty Clinical Trial Using the Next Generation Single Port Robotic Surgical System

CUHK Successfully Conducted the World’s First Multi-Specialty Clinical Trial Using the Next Generation Single Port Robotic Surgical System

Surgical advancement
CUHK Pioneers Early Lung Cancer Treatment with Hybrid Operating Room Image Guided Electromagnetic Navigation Bronchoscopy

CUHK Pioneers Early Lung Cancer Treatment with Hybrid Operating Room Image Guided Electromagnetic Navigation Bronchoscopy

Surgical advancement
Joint Study by CUHK and HKSH Reveals Patients with Comorbid REM Sleep Behavior Disorder and Depression may Suffer from Early-stage Neurodegeneration

Joint Study by CUHK and HKSH Reveals Patients with Comorbid REM Sleep Behavior Disorder and Depression may Suffer from Early-stage Neurodegeneration

Research
CUHK Succeeds in Treating Gastroesophageal Reflux Disease by Implantable Pulse Generator

CUHK Succeeds in Treating Gastroesophageal Reflux Disease by Implantable Pulse Generator

Surgical advancement
Risk of Diabetes Patients Having Depression Doubles That of the General Public CUHK Advocates Timely Assessment of Diabetes Patients’ Mental Health Conditions

Risk of Diabetes Patients Having Depression Doubles That of the General Public CUHK Advocates Timely Assessment of Diabetes Patients’ Mental Health Conditions

Research
Bowel Cancer Will Become Top Cancer in Hong Kong CUHK Introduces Colon Pill Camera to Prevent Bowel Cancer

Bowel Cancer Will Become Top Cancer in Hong Kong CUHK Introduces Colon Pill Camera to Prevent Bowel Cancer

Surgical advancement
CU Medicine study reveals increasing cognitive activity participation strengthens brain network

CU Medicine study reveals increasing cognitive activity participation strengthens brain network

Research
CUHK and HKU jointly develop a potential new treatment for brain tumours and Parkinson’s disease

CUHK and HKU jointly develop a potential new treatment for brain tumours and Parkinson’s disease

Research
CU Medicine proves AI-assisted colonoscopy increases adenoma detection rate by 40%, and  trains a new AI platform to assist early-stage gastrointestinal cancer treatment

CU Medicine proves AI-assisted colonoscopy increases adenoma detection rate by 40%, and trains a new AI platform to assist early-stage gastrointestinal cancer treatment

Surgical advancement
CU Medicine proves a new endoscopic gastrointestinal bypass is superior to conventional treatment for patients with malignant stomach outlet obstruction

CU Medicine proves a new endoscopic gastrointestinal bypass is superior to conventional treatment for patients with malignant stomach outlet obstruction

Research
CUHK announces survey results on the mental health of local child, adolescent and elderly populations

CUHK announces survey results on the mental health of local child, adolescent and elderly populations

Research
CU Medicine and Olympus Corporation sign MoU to develop  innovative endoscopy and laparoscopy technologies

CU Medicine and Olympus Corporation sign MoU to develop innovative endoscopy and laparoscopy technologies

Surgical advancement
CU Medicine proves a new ultrasound-guided endoscopic procedure has higher success and shorter procedural time for treating malignant distal biliary obstruction

CU Medicine proves a new ultrasound-guided endoscopic procedure has higher success and shorter procedural time for treating malignant distal biliary obstruction

Research
CUHK study shows control of lipid levels is crucial  to prevent cardiac events after coronary artery bypass graft

CUHK study shows control of lipid levels is crucial to prevent cardiac events after coronary artery bypass graft

Research
CUHK supports World Sleep Day 2023 Calls for attention to adverse effects of sleep problems, including increased risk of long COVID, mental and cardiovascular problems

CUHK supports World Sleep Day 2023 Calls for attention to adverse effects of sleep problems, including increased risk of long COVID, mental and cardiovascular problems

Research
CUHK performs world’s first robotic-assisted bronchoscopic  microwave ablation of lung metastases

CUHK performs world’s first robotic-assisted bronchoscopic microwave ablation of lung metastases

Surgical advancement
CU Medicine first in Asia to perform one-stage hybrid aortic arch surgery on patients with multi-segment thoracic aortic diseases using novel device

CU Medicine first in Asia to perform one-stage hybrid aortic arch surgery on patients with multi-segment thoracic aortic diseases using novel device

Research
Study led by CUHK shows robotic-assisted bladder removal with intracorporeal urinary diversion reduces blood loss and enhances post-operative recovery

Study led by CUHK shows robotic-assisted bladder removal with intracorporeal urinary diversion reduces blood loss and enhances post-operative recovery

Research
CUHK and HKBU Launch Spermine Risk Score for Prostate Cancer Diagnosis

CUHK and HKBU Launch Spermine Risk Score for Prostate Cancer Diagnosis

Research
CUHK Identifies Outcome Indicators for Benign Prostatic Hyperplasia Patients Receiving Prostatic Artery Embolisation

CUHK Identifies Outcome Indicators for Benign Prostatic Hyperplasia Patients Receiving Prostatic Artery Embolisation

Research
CU Medicine Studies Highlight Smoking as a Contributing Factor for Bladder Cancer and  Develop an International Collaborative Consensus on En Bloc Resection to Treat the Disease

CU Medicine Studies Highlight Smoking as a Contributing Factor for Bladder Cancer and Develop an International Collaborative Consensus on En Bloc Resection to Treat the Disease

Research
CUHK Successfully Performed World’s First Colorectal Endoscopic Submucosal Dissection  Using Flexible Endoscopic Robotic System

CUHK Successfully Performed World’s First Colorectal Endoscopic Submucosal Dissection Using Flexible Endoscopic Robotic System

Surgical advancement
Most Deaths from COVID-19 in Hong Kong are of 60 Years Old or Above CUHK Initiated International Effort in Devising Strategies to Protect Older People with Dementia amid COVID-19 Pandemic

Most Deaths from COVID-19 in Hong Kong are of 60 Years Old or Above CUHK Initiated International Effort in Devising Strategies to Protect Older People with Dementia amid COVID-19 Pandemic

Research
CUHK Study Proves Ablative Chemoembolization Doubles the Progression-Free Survival for Liver Cancer Patients

CUHK Study Proves Ablative Chemoembolization Doubles the Progression-Free Survival for Liver Cancer Patients

Research
CUHK-DGIST-ETH Zurich Establish Joint Laboratory on Nano-technology for Gastrointestinal and Cardiovascular Diseases

CUHK-DGIST-ETH Zurich Establish Joint Laboratory on Nano-technology for Gastrointestinal and Cardiovascular Diseases

International collaboration
World’s First Large-scale Epidemiological Survey on Adolescents by CUHK Reveals Abuse of Methamphetamine Associated with Increased Risk of Developing Lower Urinary Tract Symptoms

World’s First Large-scale Epidemiological Survey on Adolescents by CUHK Reveals Abuse of Methamphetamine Associated with Increased Risk of Developing Lower Urinary Tract Symptoms

Clinical service
CUHK World’s First Study Confirms A New Colorectal Cancer High Risk Group

CUHK World’s First Study Confirms A New Colorectal Cancer High Risk Group

Research
CUHK’s New Prostatic Artery Embolization Shows 90% Success Rate in Relieving Symptoms of Benign Prostatic Hyperplasia

CUHK’s New Prostatic Artery Embolization Shows 90% Success Rate in Relieving Symptoms of Benign Prostatic Hyperplasia

Clinical service
CUHK Survey Reveals Majority of School Teens Have Insufficient Sleep

CUHK Survey Reveals Majority of School Teens Have Insufficient Sleep

Health Campaign
CUHK Research Indicates Acupuncture can Improve Cognitive Functions of Elderly - More Elderly Participants to be Recruited for Further Investigation

CUHK Research Indicates Acupuncture can Improve Cognitive Functions of Elderly - More Elderly Participants to be Recruited for Further Investigation

Research
CUHK Assessed and Treated Over 300 Young Ketamine Abusers with Urinary Tract Dysfunction Latest Research Reveals Effectiveness of Integrated Anti-inflammatory Therapy

CUHK Assessed and Treated Over 300 Young Ketamine Abusers with Urinary Tract Dysfunction Latest Research Reveals Effectiveness of Integrated Anti-inflammatory Therapy

Research
CUHK Research Reveals that Physical and Cognitive Activities can Maintain and Improve Brain Functions of Patients with Mild Cognitive Impairments

CUHK Research Reveals that Physical and Cognitive Activities can Maintain and Improve Brain Functions of Patients with Mild Cognitive Impairments

Research
CUHK-PWH Hybrid Cardiovascular Operating Theatre Officially Opens Multi-functional Setting Enhances Surgical Outcomes

CUHK-PWH Hybrid Cardiovascular Operating Theatre Officially Opens Multi-functional Setting Enhances Surgical Outcomes

Clinical service
CUHK Proves a Non-invasive Technology Can Successfully Cure Cerebral Arteriovenous Malformation

CUHK Proves a Non-invasive Technology Can Successfully Cure Cerebral Arteriovenous Malformation

Clinical service
CUHK Urges Widespread Helmet Use and Protective Measures Against Cycling-related Traumatic Brain Injury

CUHK Urges Widespread Helmet Use and Protective Measures Against Cycling-related Traumatic Brain Injury

Research
CUHK's Youth Urological Treatment Centre Opens Today Territory's First Centre to Provide Urological Assessment and Treatment to Young Drug Abusers

CUHK's Youth Urological Treatment Centre Opens Today Territory's First Centre to Provide Urological Assessment and Treatment to Young Drug Abusers

Donation
CUHK Launches Territory-wide Sleep Health Education Campaign to Promote Healthy Sleep and Healthy School Life

CUHK Launches Territory-wide Sleep Health Education Campaign to Promote Healthy Sleep and Healthy School Life

Health Campaign
CUHK Discovers the Environmental Factors in Family and School Behind Constipation in HK Children

CUHK Discovers the Environmental Factors in Family and School Behind Constipation in HK Children

Research
'Technologies Enhancing Patient Care in the Community' CUHK Kicks Off Public Education Programme to Showcase Achievements in Computer Assisted Surgery and Clinical Management

'Technologies Enhancing Patient Care in the Community' CUHK Kicks Off Public Education Programme to Showcase Achievements in Computer Assisted Surgery and Clinical Management

Health Campaign
CUHK Discovers Drug Dosage Brings Negative Impact on Bladder Function among Young People

CUHK Discovers Drug Dosage Brings Negative Impact on Bladder Function among Young People

Research

Our Expert List

Many experts under the Faculty of Medicine are available for media interview.
Please click here for the expert list or contact us.