Search
What are you looking for?
Start main content

Press Releases

Press Releases

https://www.med.cuhk.edu.hk/press-releases/cuhk-proves-efficacy-of-home-based-management-approach-of-obstructive-sleep-apnoea-applicable-to-50-of-public-hospital-adult-cases-with-waiting-time-reduced-by-80
https://www.med.cuhk.edu.hk/press-releases/cuhk-proves-efficacy-of-home-based-management-approach-of-obstructive-sleep-apnoea-applicable-to-50-of-public-hospital-adult-cases-with-waiting-time-reduced-by-80

CUHK Proves Efficacy of Home-Based Management Approach of Obstructive Sleep Apnoea Applicable to 50% of Public Hospital Adult Cases with Waiting Time Reduced by 80%

The Faculty of Medicine at The Chinese University of Hong Kong (CUHK) studied and compared two different approaches of diagnosis and management of obstructive sleep apnoea (OSA).  The study proves that the ambulatory approach is non-inferior to the conventional hospital-based practice, but the former offers greater overall benefits to adult patients by shortening 80% waiting time and substantially lowering medical costs.  The findings have been recently published in the international scientific journal Nature – Scientific Reports.  

 

Untreated OSA increases risk of cardiovascular diseases

OSA is a common form of sleep-disordered breathing.  When the patient sleeps, the upper airway is obstructed which leads to a reduction of oxygen in the blood, hence causing sleep fragmentation, disabling daytime sleepiness and impaired cognitive function.  Untreated patients bear a higher risk of cardiovascular diseases, such as heart failure or stroke.  According to studies, the prevalence rate of OSA among middle-aged men is 5% and 2-3% for women.

 

Dr Susanna So Shan NG, Clinical Assistant Professor (Honorary), Department of Medicine and Therapeutics at CUHK said, ‘Ageing, male, obesity, craniofacial factors such as small chin, enlarged tonsils, large neck size are all risk factors of OSA.’

 

Diagnosis and treatment of OSA

The Apnoea-hypopnea index (AHI) is used to reflect the severity of OSA.  It is a count of the number of upper airway obstructions per hour of sleep, with 5 to 15 events being mild and 15 to 30 moderate.  More than 30 events is considered severe.

 

Sleep tests are used to diagnose OSA, in which a machine will be used to measure patients’ oxygen saturation, airflow, respiratory effort, as well as other indexes including body position, snoring, heart rate.  Continuous positive airway pressure (CPAP) is a common therapy which helps to prevent airway closure during sleep and hence to improve patients’ sleep quality, cognitive function and blood pressure, but it has to be used continuously during sleep.  Depending on the severity, other treatment options include dental device and surgery.

 

The conventional sleep test, namely polysomnography, is hospital-based and is used in most public hospitals in Hong Kong.  However, limited beds and medical resources could mean a lengthy waiting period of up to 12 months.  The home-based sleep test is an alternative available in Hong Kong for only a few years that allows adult patients to do the test at home with a portable device provided by specialists.  Currently 40% of adults attending the Respiratory Clinic of the Prince of Wales Hospital with OSA symptoms are referred to the Faculty and are using this service.

 

Study shows home-based approach can cut 80% waiting time and reduce medical expenses

In order to study and compare the efficacy of the two approaches in managing OSA, the Faculty of Medicine at CUHK recruited 316 new referrals with OSA symptoms between September 2013 and August 2014, dividing them into two groups: home-sleep-study group and hospital-based group.

 

Prof. David Shu Cheong HUI, Chairman and Stanley Ho Professor of Respiratory Medicine, Department of Medicine and Therapeutics at CUHK, stated, ‘Our results showed that the home-based approach outperformed the conventional method in all aspects.  Patients had greater improvement in daytime sleepiness and quality of life, and showed better cognitive function.  Besides, these patients tended to be more adherent to CPAP treatment and had a higher usage per night.  I believe patients may feel more relaxed in their home setting and thus a better therapeutic effect is yielded.’

 

Comparison of waiting time of the ‘home-sleep-study’ group and ‘hospital-based’ group:

 

 Home basedHospital based
Received sleep test157 patients159 patients
Waiting time between 1st consultation to diagnostic sleep test59 days249 days
 
Diagnosed with moderate to severe OSA (AHI≥15),received and completed 3-month CPAP treatment86 patients86 patients
Waiting time between 1st consultation to CPAP titration117 days266 days
Waiting time between 1st consultation to CPAP treatment155 days300 days

 

The results showed that the ambulatory home-based sleep test approach could reduce 6 months, i.e. 80%, of waiting time.  The waiting time for CPAP titration and CPAP treatment is also reduced by 5 months.  It is estimated that the new approach can save almost HK$14,000 medical costs for each adult patient compared to the hospital-based approach.

 

Professor Hui concluded, ‘From our experience, the ambulatory sleep test machine and ambulatory CPAP devices are very user-friendly.  Patients can easily manage the operation of the device at home following simple instructions from the medical staff.  A shorter waiting time is crucial to OSA patients which may lower their risk of cardiovascular diseases caused by delayed treatment. The American Academy of Sleep Medicine has recently issued a new guideline[1] this year, recommending the use of home sleep apnoea testing for adult patients with signs and symptoms that indicate moderate to severe OSA.  We estimate that half of the public hospital patients with OSA in Hong Kong can benefit from this ambulatory approach, but not including the complicated cases.  Since the complexity of OSA varies in different cases, professional medical advices are crucial throughout diagnosis and treatment.’


[1] American Academy of Sleep Medicine Clinical Practice Guideline

http://www.aasmnet.org/Resources/clinicalguidelines/diagnostic-testing-OSA.pdf

 

A recent study led by Prof. David Shu Cheong HUI (right), Chairman and Stanley Ho Professor of Respiratory Medicine, Department of Medicine and Therapeutics, and Dr Susanna So Shan NG, Clinical Assistant Professor (Honorary), Department of Medicine and Therapeutics, CUHK Faculty of Medicine, proves that the ambulatory approach of managing obstructive sleep apnoea (OSA) can shorten 80% waiting time and substantially lower medical costs.

A recent study led by Prof. David Shu Cheong HUI (right), Chairman and Stanley Ho Professor of Respiratory Medicine, Department of Medicine and Therapeutics, and Dr Susanna So Shan NG, Clinical Assistant Professor (Honorary), Department of Medicine and Therapeutics, CUHK Faculty of Medicine, proves that the ambulatory approach of managing obstructive sleep apnoea (OSA) can shorten 80% waiting time and substantially lower medical costs.

 

 Madam Tsoi (right) had undergone home sleep test study and was diagnosed with moderate OSA. She finds the ambulatory devices easy to operate with comprehensive instructions given by medical staff.

Madam Tsoi (right) had undergone home sleep test study and was diagnosed with moderate OSA. She finds the ambulatory devices easy to operate with comprehensive instructions given by medical staff.

Mr Kong with severe OSA says his daytime sleepiness problem has been eased after continuous positive airway pressure (CPAP) treatment. His sleep quality has also been improved.

Mr Kong with severe OSA says his daytime sleepiness problem has been eased after continuous positive airway pressure (CPAP) treatment. His sleep quality has also been improved.

More Press Releases

CUHK Study Suggests Preoperative Screening for Obstructive Sleep Apnoea to  Lower Risk of Postoperative Cardiovascular Events

CUHK Study Suggests Preoperative Screening for Obstructive Sleep Apnoea to Lower Risk of Postoperative Cardiovascular Events

Research
Asia’s First Research by CUHK on Patients’ Lifestyle Reveals Personalised Modification Programme Effective in Reducing Severity of OSA

Asia’s First Research by CUHK on Patients’ Lifestyle Reveals Personalised Modification Programme Effective in Reducing Severity of OSA

Research
CUHK Conducts World’s First Family Study on Rapid Eye Movement Sleep Behaviour Disorder to Investigate Familial Link with Parkinson’s Disease

CUHK Conducts World’s First Family Study on Rapid Eye Movement Sleep Behaviour Disorder to Investigate Familial Link with Parkinson’s Disease

Research
CUHK Highlights the Significance of Hospital Infection Control System in Controlling MERS

CUHK Highlights the Significance of Hospital Infection Control System in Controlling MERS

Research
CUHK Research Findings on Severe Human Swine Flu in Hong Kong

CUHK Research Findings on Severe Human Swine Flu in Hong Kong

Research
A Global Study Led by CU Medicine and HKUMed Discovers  a Hepatitis C Virus Drug as Potent Treatment for COVID-19

A Global Study Led by CU Medicine and HKUMed Discovers a Hepatitis C Virus Drug as Potent Treatment for COVID-19

Research
40% of Hong Kong People Show Gut Dysbiosis Comparable to that of COVID-19 Patients CUHK Microbiome Immunity Formula Hastens Recovery of COVID-19 Patients and Offers Hope to Boost Immunity

40% of Hong Kong People Show Gut Dysbiosis Comparable to that of COVID-19 Patients CUHK Microbiome Immunity Formula Hastens Recovery of COVID-19 Patients and Offers Hope to Boost Immunity

Research
CUHK and International Experts in Diabetes Care Joined Hands for Four Years Developing a Multicomponent, Integrated Strategy for Diabetes under The Lancet

CUHK and International Experts in Diabetes Care Joined Hands for Four Years Developing a Multicomponent, Integrated Strategy for Diabetes under The Lancet

International collaboration
CU Medicine Studies Reveal Diabetes Death and Complication Rates Declining - but Not in the Young

CU Medicine Studies Reveal Diabetes Death and Complication Rates Declining - but Not in the Young

Research
CU Medicine Study Shows Liver Injury is Common and Prognostic in COVID-19 Patients

CU Medicine Study Shows Liver Injury is Common and Prognostic in COVID-19 Patients

Research
CUHK Finds that the Coronavirus Can Persist in Stool after Its Clearance in Respiratory Tract Will Conduct Stool Test for People in Quarantine Camps for Early Identification

CUHK Finds that the Coronavirus Can Persist in Stool after Its Clearance in Respiratory Tract Will Conduct Stool Test for People in Quarantine Camps for Early Identification

Research
CU Medicine Announces the Community Response Study Results During the Early Phase of the COVID-19 Outbreak in Hong Kong

CU Medicine Announces the Community Response Study Results During the Early Phase of the COVID-19 Outbreak in Hong Kong

Research
Inaugural Collaboration between CUHK and AstraZeneca on Diabetic Kidney Disease Research Advancing a Global Strategy Against Diabetic Kidney Disease

Inaugural Collaboration between CUHK and AstraZeneca on Diabetic Kidney Disease Research Advancing a Global Strategy Against Diabetic Kidney Disease

International collaboration
Chinese Women with Polycystic Ovarian Syndrome have 4-fold Higher Risk of Developing Diabetes

Chinese Women with Polycystic Ovarian Syndrome have 4-fold Higher Risk of Developing Diabetes

Research
Multicomponent Frailty Prevention Programme Reduces Frailty Over 80% of Pre-frail Elderly Reverse to Robust Phenotype

Multicomponent Frailty Prevention Programme Reduces Frailty Over 80% of Pre-frail Elderly Reverse to Robust Phenotype

Research
CUHK Launches a Population-based Programme to Evaluate and Track Brain Health Status  of 5,000 Hong Kong Residents for Free

CUHK Launches a Population-based Programme to Evaluate and Track Brain Health Status of 5,000 Hong Kong Residents for Free

Research
CUHK Establishes Margaret K.L. Cheung Research Centre for Management of Parkinsonism  To Develop Innovative Solutions to Slow Disease Progression

CUHK Establishes Margaret K.L. Cheung Research Centre for Management of Parkinsonism To Develop Innovative Solutions to Slow Disease Progression

Research
CUHK Study Proves Low-Dose Tricyclic Antidepressant (TCA) Effective in Treating Patients with Refractory Functional Dyspepsia

CUHK Study Proves Low-Dose Tricyclic Antidepressant (TCA) Effective in Treating Patients with Refractory Functional Dyspepsia

Research
CUHK Study Reveals 1 in 6 Diabetic Patients Project Rapid Renal Function Decline

CUHK Study Reveals 1 in 6 Diabetic Patients Project Rapid Renal Function Decline

Research
CUHK Studies Alert Mothers to Pregnancy Weight Gain

CUHK Studies Alert Mothers to Pregnancy Weight Gain

Research
CUHK Study Proves Achieving Sustained Minimal Disease Activity Lowers the Risk of Cardiovascular Diseases in Psoriatic Arthritis Patients

CUHK Study Proves Achieving Sustained Minimal Disease Activity Lowers the Risk of Cardiovascular Diseases in Psoriatic Arthritis Patients

Research
CUHK Study Sees Increasing Global Incidence of Colorectal Cancer Among Younger People

CUHK Study Sees Increasing Global Incidence of Colorectal Cancer Among Younger People

Research
CUHK Pioneers in Developing Standardised Tests for Screening Cognitive Impairment in the Ageing Population in Hong Kong

CUHK Pioneers in Developing Standardised Tests for Screening Cognitive Impairment in the Ageing Population in Hong Kong

Clinical service
CUHK Discovers an Essential Oncogene in Non-Alcoholic Fatty Liver Disease-Associated Hepatocellular Carcinoma

CUHK Discovers an Essential Oncogene in Non-Alcoholic Fatty Liver Disease-Associated Hepatocellular Carcinoma

Research
CUHK Study Reveals Patients with Recovery of Hepatitis B Still at Risk of Liver Cancer

CUHK Study Reveals Patients with Recovery of Hepatitis B Still at Risk of Liver Cancer

Research
CUHK Announces World’s First Systematic Review of the Global Incidence and Prevalence of Inflammatory Bowel Diseases in the 21st Century Reveals Surge in Hong Kong in past 30 years

CUHK Announces World’s First Systematic Review of the Global Incidence and Prevalence of Inflammatory Bowel Diseases in the 21st Century Reveals Surge in Hong Kong in past 30 years

Research
CUHK Launches World’s First Study Utilizing Retinal Imaging for Alzheimer’s Disease Screening in Chinese Population

CUHK Launches World’s First Study Utilizing Retinal Imaging for Alzheimer’s Disease Screening in Chinese Population

Research
CUHK Sees Atrial Fibrillation-related Stroke Cases 3 Times Higher Over 15 Years

CUHK Sees Atrial Fibrillation-related Stroke Cases 3 Times Higher Over 15 Years

Research
CUHK Announces World’s First Meta-analysis on Prevalence of Helicobacter pylori Infection

CUHK Announces World’s First Meta-analysis on Prevalence of Helicobacter pylori Infection

Research
CUHK Recommends Oral Glucose Tolerance Test for All Pregnant Women Study Reveals Children of Women with Gestational Diabetes Mellitus Have 3-Fold Diabetes Risk

CUHK Recommends Oral Glucose Tolerance Test for All Pregnant Women Study Reveals Children of Women with Gestational Diabetes Mellitus Have 3-Fold Diabetes Risk

Research
CUHK Collaborates with Australian Experts to Untangle Mystery of Eastern Inflammatory Bowel Disease Gut Microbiota

CUHK Collaborates with Australian Experts to Untangle Mystery of Eastern Inflammatory Bowel Disease Gut Microbiota

Research
CUHK Reveals Non-Alcoholic Fatty Liver Disease Afflicts Even the Non-Obese

CUHK Reveals Non-Alcoholic Fatty Liver Disease Afflicts Even the Non-Obese

Research
CUHK Professor Receives World Honour For Stroke Services Pioneering an Innovative 3-in-1 Multi-Target Therapy to Repair Damaged Brain After Stroke and Enhance Functional Recovery

CUHK Professor Receives World Honour For Stroke Services Pioneering an Innovative 3-in-1 Multi-Target Therapy to Repair Damaged Brain After Stroke and Enhance Functional Recovery

Awards and honors
CUHK Discovers Fatty Liver Causing Severe Liver Fibrosis or Cirrhosis in 1 Out of 5 Diabetic Patients

CUHK Discovers Fatty Liver Causing Severe Liver Fibrosis or Cirrhosis in 1 Out of 5 Diabetic Patients

Research
CUHK Opens Therese Pei Fong Chow Research Centre for Prevention of Dementia and Establishes a One-stop Online Platform to Provide Information on Dementia

CUHK Opens Therese Pei Fong Chow Research Centre for Prevention of Dementia and Establishes a One-stop Online Platform to Provide Information on Dementia

Research
CUHK World’s First Study Confirms A New Colorectal Cancer High Risk Group

CUHK World’s First Study Confirms A New Colorectal Cancer High Risk Group

Research
CUHK Sets up the Global First Research Registry on Early Onset Dementia in Chinese Population

CUHK Sets up the Global First Research Registry on Early Onset Dementia in Chinese Population

Research
CUHK and HKU Researchers Introduce 3D Printing Technology in Complex Cardiac Surgery Procedures

CUHK and HKU Researchers Introduce 3D Printing Technology in Complex Cardiac Surgery Procedures

Research
CUHK Jointly Discovers New Therapeutic Solution for Minor Stroke in Global Study with over 30 Countries

CUHK Jointly Discovers New Therapeutic Solution for Minor Stroke in Global Study with over 30 Countries

Research
CUHK Sees Early Evaluation of TIA Patients Reduce Rate of Stroke by 70% in a Global Study of 21 Countries

CUHK Sees Early Evaluation of TIA Patients Reduce Rate of Stroke by 70% in a Global Study of 21 Countries

Research
CUHK Conducts Hong Kong’s First Study on Seven Common Respiratory Viruses Revealing Respiratory Syncytial Virus and Influenza A as Prevalent Fatal Types

CUHK Conducts Hong Kong’s First Study on Seven Common Respiratory Viruses Revealing Respiratory Syncytial Virus and Influenza A as Prevalent Fatal Types

Research
CUHK Screening Reveals 1 in 3 Older Adults in Community Suffer Brain Small Vessel Disease, Early Prevention Recommended

CUHK Screening Reveals 1 in 3 Older Adults in Community Suffer Brain Small Vessel Disease, Early Prevention Recommended

Clinical service
CUHK Latest Research Reveals FMT Effectiveness Triples that of Conventional Treatment

CUHK Latest Research Reveals FMT Effectiveness Triples that of Conventional Treatment

Research
CUHK Introduces High Frequency Oscillations to Determine Resection Margin Increases the Effectiveness of Complex Epilepsy Surgery by around 30%

CUHK Introduces High Frequency Oscillations to Determine Resection Margin Increases the Effectiveness of Complex Epilepsy Surgery by around 30%

Surgical advancement
CUHK Advocates Stringent Control of Cardiovascular Risks for Reopening of Narrowed Brain Arteries - A New Paradigm to Prevent Recurrent Stroke (Available in Chinese only)

CUHK Advocates Stringent Control of Cardiovascular Risks for Reopening of Narrowed Brain Arteries - A New Paradigm to Prevent Recurrent Stroke (Available in Chinese only)

Research
CUHK Latest Research Reveals over 100,000 New Non-alcoholic Fatty Liver Cases in Hong Kong Annually

CUHK Latest Research Reveals over 100,000 New Non-alcoholic Fatty Liver Cases in Hong Kong Annually

Research
CUHK Study Reveals Peer Support Can Reduce Hospital Admission of Distressed Diabetes Patients

CUHK Study Reveals Peer Support Can Reduce Hospital Admission of Distressed Diabetes Patients

Research
Joint Study by CUHK and HKSH Reveals Patients with Comorbid REM Sleep Behavior Disorder and Depression may Suffer from Early-stage Neurodegeneration

Joint Study by CUHK and HKSH Reveals Patients with Comorbid REM Sleep Behavior Disorder and Depression may Suffer from Early-stage Neurodegeneration

Research
CUHK Advocates Atrial Fibrillation Screening and Drug Education to Reduce Risk of Stroke among Elderly

CUHK Advocates Atrial Fibrillation Screening and Drug Education to Reduce Risk of Stroke among Elderly

Clinical service
Screening Reveals Over 50% Community-dwelling Population Aged 65 or above are Pre-frail

Screening Reveals Over 50% Community-dwelling Population Aged 65 or above are Pre-frail

Research
Risk of Diabetes Patients Having Depression Doubles That of the General Public CUHK Advocates Timely Assessment of Diabetes Patients’ Mental Health Conditions

Risk of Diabetes Patients Having Depression Doubles That of the General Public CUHK Advocates Timely Assessment of Diabetes Patients’ Mental Health Conditions

Research
Radiotherapy to Head and Neck Raises Risk for Stroke CUHK Proved Effectiveness of Carotid Angioplasty and Stenting

Radiotherapy to Head and Neck Raises Risk for Stroke CUHK Proved Effectiveness of Carotid Angioplasty and Stenting

Research
CUHK and PolyU Jointly Introduce TeleStroke for 24-hour Thrombolysis Service at Prince of Wales Hospital

CUHK and PolyU Jointly Introduce TeleStroke for 24-hour Thrombolysis Service at Prince of Wales Hospital

Clinical service
CUHK Releases Research Results on Employment Status of Hong Kong Chronic Kidney Disease (CKD) Dialysis Patients and Promotes Predialysis Education Programme for Mid to Late Stage CKD patients

CUHK Releases Research Results on Employment Status of Hong Kong Chronic Kidney Disease (CKD) Dialysis Patients and Promotes Predialysis Education Programme for Mid to Late Stage CKD patients

Research
CUHK Conducts Asia's Largest Clinical Study on Life-threatening Infections caused by RSV and Influenza in Hong Kong Adults and Elderly

CUHK Conducts Asia's Largest Clinical Study on Life-threatening Infections caused by RSV and Influenza in Hong Kong Adults and Elderly

Research
CUHK Announces Latest Medical Treatment for Minor Stroke

CUHK Announces Latest Medical Treatment for Minor Stroke

Research
Hong Kong and Macau Among Top Three Regions in Asia-Pacific with the Highest Incidence of Inflammatory Bowel Disease CUHK Establishes Registry to Increase Public Awareness

Hong Kong and Macau Among Top Three Regions in Asia-Pacific with the Highest Incidence of Inflammatory Bowel Disease CUHK Establishes Registry to Increase Public Awareness

Research
CUHK-HCC Score Accurately Predicts Risk of Liver Cancer in Chronic Hepatitis B Patients Receiving Antiviral Therapy

CUHK-HCC Score Accurately Predicts Risk of Liver Cancer in Chronic Hepatitis B Patients Receiving Antiviral Therapy

Research
CUHK and Shanghai Jiao Tong University Discover Genetic Predictor of Diabetes in Chinese Patients

CUHK and Shanghai Jiao Tong University Discover Genetic Predictor of Diabetes in Chinese Patients

Research
CUHK Pioneers the Use of 3D Echocardiography to Identify At-Risk Mitral Valve Prolapse Patients

CUHK Pioneers the Use of 3D Echocardiography to Identify At-Risk Mitral Valve Prolapse Patients

Research
CUHK will hold 'SARS A Decade On: A Conference for the Health Professionals'

CUHK will hold 'SARS A Decade On: A Conference for the Health Professionals'

Symposium
CUHK Advocates Palliative Care for Advanced Dementia Patients with Swallowing Problems

CUHK Advocates Palliative Care for Advanced Dementia Patients with Swallowing Problems

Research
CUHK Study Reveals High Salt Intake Will Lead to High Blood Pressure and Higher Risk of Stroke

CUHK Study Reveals High Salt Intake Will Lead to High Blood Pressure and Higher Risk of Stroke

Research
CUHK Launches Territory-wide Sleep Health Education Campaign to Promote Healthy Sleep and Healthy School Life

CUHK Launches Territory-wide Sleep Health Education Campaign to Promote Healthy Sleep and Healthy School Life

Health Campaign
CUHK and HKU's Collaborative Research Discovers Novel Epilepsy Genetic Markers

CUHK and HKU's Collaborative Research Discovers Novel Epilepsy Genetic Markers

Research
CUHK Advocates Early Detection of Chronic Kidney Diseases Joined by Leading Nephrologists to Make Sound Recommendations

CUHK Advocates Early Detection of Chronic Kidney Diseases Joined by Leading Nephrologists to Make Sound Recommendations

Research
CUHK Proves the Potent Efficacy of Stenting for Carotid Artery Narrowing and Cardiac Contractility Modulation for Heart Failure

CUHK Proves the Potent Efficacy of Stenting for Carotid Artery Narrowing and Cardiac Contractility Modulation for Heart Failure

Research
Three CUHK Scholars Named Croucher Senior Research Fellow 2011-12

Three CUHK Scholars Named Croucher Senior Research Fellow 2011-12

Awards and honors

Our Expert List

Many experts under the Faculty of Medicine are available for media interview.
Please click here for the expert list or contact us.